吴峻立，主任医师，副教授，硕士生导师。研究方向为胰腺肿瘤综合治疗。现为南京医科大学第一附属医院普外科主任医师、南京医科大学副教授。致力于普外科临床、教学和科研工作 15 年，从事胰腺外科专业 12 年，每年参与完成 150 余例各类胰腺手术，积极参与国内外胰腺外科专业学术交流，参编多篇外科论著。
2010年获得卫生部“第一届全国高等医学院校大学生临床技能竞赛”一等奖（排名第 2）；2011年获得卫生部“第二届全国高等医学院校大学生临床技能竞赛”获得二等奖（排名第 2）；“ 实体肿瘤射频原位灭活的实验及临床研究” 获 2006 年江苏省科技进步一等奖（名第 8）；“重症急性胰腺炎中枢神经系统功能障碍的系列研究” 获得 2008 年南京市科学技术进步三等奖（排名第 5）；“实体肿瘤射频原位灭活的实验和临床研究”获得 2009 年中华医学科技三等奖（排名第 7）； “胰腺癌基础及临床研究”获得 2012 年教育部科技进步二等奖（排名第 10）。
作为一名临床一线胰腺外科医师，参与 10 多项科研项目，其中“国家重大支撑项目十一五计划”子课题、国家自然科学基金项目多项。
主要学术论著
1. Wu J, Guo F, Wei J, et al. [Surgicaltreatment for pancreatic neuroendocrine neoplasmas]. Zhejiang da xue xue bao Yixue ban = Journal of Zhejiang University Medical sciences 2016; 45(1): 31-5.
2. Wei J, Liu X, Wu J, et al. Diagnosis andsurgical management of insulinomas in 33 consecutive patients at a singleinstitution. Langenbeck's archives of surgery 2016; 401(7): 1019-25.
3. Tu M, Lu C, Lv N, et al. Vasohibin 2 promoteshuman luminal breast cancer angiogenesis in a non-paracrine manner viatranscriptional activation of fibroblast growth factor 2. Cancer letters 2016;383(2): 272-81.
4. Qian D, Lu Z, Jackson R, et al. Effect ofantecolic or retrocolic route of gastroenteric anastomosis on delayed gastricemptying after pancreaticoduodenectomy: A meta-analysis of randomizedcontrolled trials. Pancreatology : official journal of the InternationalAssociation of Pancreatology (IAP) [etal] 2016; 16(1): 142-50.
5. Lu Z, Yin J, Wei J, et al. Small amounts oftissue preserve pancreatic function: Long-term follow-up study ofmiddle-segment preserving pancreatectomy. Medicine 2016; 95(46): e5274.
6. Huo X, Wei J, Liu X, et al. Brunner's glandcyst in combination with gastrointestinal stromal tumor: A case report.Oncology letters 2016; 11(5): 3409-12.
7. Gao W, Dai X, Dai C, et al. Comparison ofpatency rates and clinical impact of different reconstruction methods followingportal/superior mesenteric vein resection during pancreatectomy. Pancreatology: official journal of the International Association of Pancreatology (IAP) [et al] 2016; 16(6): 1113-23.
8. Wei J, Liu X, Wu J, et al. Modified One-layerDuct-to-mucosa Pancreaticojejunostomy Reduces Pancreatic Fistula AfterPancreaticoduodenectomy. International surgery 2015.
9. Wei J, Lin S, Wang C, et al. Glucagonomasyndrome: A case report. Oncology letters 2015; 10(2): 1113-6.
10. Chen J, Li Q, An Y, et al. CEACAM6 inducesepithelial-mesenchymal transition and mediates invasion and metastasis inpancreatic cancer. International journal of oncology 2013; 43(3): 877-85.
11. An Y, Cai B, Chen J, et al. MAP3K10 promotesthe proliferation and decreases the sensitivity of pancreatic cancer cells togemcitabine by upregulating Gli-1 and Gli-2. Cancer letters 2013; 329(2):228-35.
12. Zhang Y, Wei J, Wang H, et al. Epithelialmesenchymal transition correlates with CD24+CD44+ and CD133+ cells inpancreatic cancer. Oncology reports 2012; 27(5): 1599-605.
13. Wang H, Wu J, Zhang Y, et al. Transforminggrowth factor beta-induced epithelial-mesenchymal transition increases cancerstem-like cells in the PANC-1 cell line. Oncology letters 2012; 3(1): 229-33.
14. Xue X, Lu Z, Tang D, et al. Galectin-1 secretedby activated stellate cells in pancreatic ductal adenocarcinoma stroma promotesproliferation and invasion of pancreatic cancer cells: an in vitro study on themicroenvironment of pancreatic ductal adenocarcinoma. Pancreas 2011; 40(6):832-9.
15. Wu J, Wei J, Meng K, et al. Identification ofan HLA-A*0201-restrictive CTL epitope from MUC4 for applicable vaccine therapy.Immunopharmacology and immunotoxicology 2009; 31(3): 468-76.
16. Wei J, Gao W, Wu J, et al. Dendritic cellsexpressing a combined PADRE/MUC4-derived polyepitope DNA vaccine inducemultiple cytotoxic T-cell responses. Cancer biotherapy &radiopharmaceuticals 2008; 23(1): 121-8.
